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When humans arrived, they carried seeds out of the Caucasus along the Silk Route, and this is where the first fork in the genetic river occurred. The seeds that moved east into the colder regions of the Himalayas developed into the so-called indica strains, also known as kush strains; the high they produce tends to be more physical than cerebral.
1937: The [Marihuana Tax Act](https://en.wikipedia.org/wiki/Marihuana_Tax_Act_of_1937) is enacted, effectively prohibiting cannabis at the federal level. Although medical use is still permitted, new fees and regulatory requirements significantly curtail its use.
Timeline of Cannabis Laws in the United States - Wikipedia
wikipedia.org
The Times found that at least 19 people who overdosed on kratom alone had struggled with their mental health, including with depression or post-traumatic stress disorder.
Part 1: Hundreds Died Using Kratom in Florida. It Was Touted as Safe.
Tampabay.com
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