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The few who clawed their way into the ranks of officers still encountered filthy toilets, secondhand uniforms, segregated showers, and disrespect from white soldiers. And a man who survived the dangers of the battlefield courted danger by walking the streets of his hometown in uniform.

Hidden Figures

Margot Lee Shetterly

One well‐known example of findings that are reproducible but invalid is the replicated report of reduced corpus callosum size in Autism Spectrum Disorder (ASD). A meta‐analysis of these findings supported a significant group difference, yet when the raw data were gathered and assembled into a single analysis, the findings were no longer significant because that analysis included the appropriate covariation for IQ and overall brain volume—scaling effects in which larger or smaller brains have, respectively, larger or smaller regional brain volumes (Lefebvre, Beggiato, Bourgeron, & Toro, [2015](#jcpp12962-bib-0007)). The original studies from which this mega‐analysis drew produced similar findings because, in general, they similarly failed to address appropriately these potential confounds. Thus, large data sets may yield statistical significance and more statistically stable findings that improve reproducibility, yet provide little assurance of the validity of those findings.

Editorial: Data Repositories, Registries, and Standards in the Search for Valid and Reproducible Biomarkers - Peterson - 2018 - Journal of Child Psychology and Psychiatry - Wiley Online Library

onlinelibrary.wiley.com

life. Nor was he the only one warning the medical profession against hubris in the early twentieth century.

Pale Rider

Laura Spinney

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